Research. Sometimes that’s all.
Despite the need for light sensitivity and sound sensitivity and dark room.
Despite memory loss, headaches and head pressure that make you feel like you’re in a vise.
Despite the inability to concentrate.
Being told to stay away from computers and smartphones and relax your mind.
Finding the path ends everything. Research becomes usable.
Daniel Carcillo knows this all too well.
At the age of 30, the NHL promoter was forced into early retirement after his seventh diagnosis in 2015. After 429 games spanning 11 seasons, his second Stanley Cup ended his career. He spent the next four years trying to pull himself out of a debilitating battle with post-rheumatic-deflection syndrome, which eventually led him to suicide.
“Read a medical paper on the conclusion, visited [a] Brain Banks, CT Pathologist, “said Carcillo.” Doing a lot of things to manage the pathology, which is actually available to us. There is no citation-less novel, valid care option for TBI (traumatic brain injury) survivors, and it is indeed dangerous because the number 1 TBI after death is suicide after TBI. “
This is one of the biggest issues: There is no official game plan when it comes to fixing the brain. It is not a broken arm, when you know that you will be in a cast for a few weeks, then undergo physical therapy and then it is good to go. It’s a shoulder-shrug emoji – and it’s from your neurologist. It’s a “let’s take a stab at it” or “try it” because there’s no straight path. Every mind is different.
But then things changed for Carcillo nearly two years ago when he was introduced to a silocobin through an ex-teammate.
“Everyday anxiety and depression diminished in intensity,” he recalled of his symptoms after a psilocybin function, “which is a guided and monitored psychedelic experience.” On the third day I remember me at the farm without glasses Was going, which was not normal as my light sensitivity was at its peak. And then I found that I would face my wife and my children more often because I wanted to, I just couldn’t wait. To run back to hug them. I just felt more connected. I felt like my brain is picking up the fog and in a very short time there are really remarkable, remarkable things. “
It was a life-changing moment for Carcillo. He started feeling better. His symptoms began to subside as soon as he stopped at a specific protocol for loading doses (3–5 mg) and maintenance doses of psilocybin and other adaptogens. He did a qEEG (brain mapping) and bloodletting again – something that he did after every new thing to see if it was really working – and this time there were no abnormalities and that his The bloodshed was obvious.
“He was really big Aha Moment, “he recently told Sporting News during a phone interview.” Waited for about a year until I got that second clear exam and then I said, well, that’s enough data for me to go public with this. And then I just started placing the pieces of the puzzle to create this reality and build a championship team around me that I know how to play. “
That championship team is co-founded by Carcillo, a company called Vesna Health Inc., “an emerging life sciences company committed to patient empowerment and the advancement of silicobin-based medicine to improve health and well-being.” It closed on $ 4 million in financing back in January and announced the last day of the Brain Injury Awareness Month on March 31, the successful completion of the $ 16.1 CAD million further private placement to complete its Go-Public transaction Enhanced. Proceeds from the financing will be used primarily for the company’s preclinical and clinical development for psychedelic-assisted therapy for the treatment of TBI. On Wednesday, he announced George Steinbrenner IV as a new investor who is joining the board of directors.
Steinbrenner said in the company’s news release, “The great advances in science have finally given us to recognize and better understand the consequences of traumatic brain injuries, especially those occurring frequently in professional sports”. Motorsports) deal with TBI. “It is important that we continue to move forward in this area to deliver innovative treatment options that can help people overcome the neurological and psychological damage associated with that trauma.”
‘Rewire’ the mind
Psychedelic medicine has burst. The idea of natural products, such as psilocybin, is a psychedelic extract that occurs naturally in some 200 types of mushrooms and is an active ingredient in magic mushrooms, which has drawn attention to education. New York University, Johns Hopkins and Icahn School of Mount Sinai (New York) are just a few who have studied or are in the process of studying its use for the treatment of the brain when it comes after anxiety, depression, and traumatic stress disorder. .
“Oh! That is the matter [an impact on] Neuro-chemical and neurologic activity in the brain, ”Dr. of the University of Miami Miller School of Medicine. Michael E. Noted Hofer, who is studying whether using cannabidiol (CBD) and psilocybin as a pill can treat mild traumatic brain injury and PTSD.
“In other words, we know it’s not that it’s just something you take in and you think you feel different. There are definitely chemical pathways in the brain that are receptors for psilocybin or psilocybin metabolites. So there are some changes in brain activity that occur when taking this compound. “
“We know where psilocybin and its metabolites function in a brain; it is described,” Hauffer later added during an interview with Sporting News. “How those interactions unfold in different ways in the brain Yes, it is still not well understood. “
In the United States, silicobin is labeled as a Schedule I drug by the Department of Drug Enforcement. In Canada to the north, mushrooms are illegal under the Controlled Drugs and Substances Act (CDSA). But the stigma regarding medicine has reduced. Oregon, for example, passed Voting measure 109 In November psilocybin supported decriminalizing and its use as a therapeutic. In Canada, life-long patients, physicians who want to use psilocybin, are exempted. Understand how this will work for their patients And others.
This is what Carcillo and Vesana Health are focusing on. The company will soon run preclinical trials on psychedelic drug assisted therapy to treat TBI-related depression in association with the Food and Drug Administration in the United States and Health Canada.
“We have a specific protocol,” Carcillo said. “Loading doses are in large quantities, usually between three and five grams. What it does is it breaks down destructive thought patterns, stimulates areas of our brain due to emotional or physical trauma, and gives us those four Helps to move and create new neurological pathways
“On a non-hallucinatory or sub-perceptual level, you can go about your daily activities,” Carcillo said later, adding that he was on psilocybin during the interview. “You can access the language better, you can be more creative. It’s a mood elevator, and then it simply does what it does on mood and personality, not to mention what it would do to the brain Is. Then at larger doses, 3-5 grams is when you start breaking destructive thought patterns and re-illuminating your brain. “
While Carcillo, and others, are adamant that Psilocybin can help TBI survivors recover, not everyone is convinced.
Sporting News is also an Associate Professor of Psychiatry Drs. Stephen Ross and NYU reached out to the Associate Director of the Center of Psychedelic Medicine at Langone Health to discuss Psilocybin and its use for the treatment of TBI. He declined to be interviewed, but made the following statement through a media relations representative:
“Nothing is known about the use of psilocybin in the treatment of TBI. Any therapeutic effects of psychedelics for the treatment of TBI are extremely speculative – although within the scope of possibilities, some new neurobiological findings have been offered with psychedelics in terms of neurogenesis and neuroplasty. “
‘My goal is to help a million people’
As things progressed with Vesana Health, the ultimate goal for Ames’ former NHL enforcer nicknamed “Car Bomb” in more than 1,200 penalty minutes during his car, is to help people, just as he did on the ice. . He has been talking to TBI survivors for the last six years and understands what they are doing better than anyone. He understands how scary it is to face the unknown and uncertainty. They have asked the same question: will I get better? Will I be back before I get hurt? How long will my symptoms last? when will it be? How much time do I have to pay?
Carcillo knows all about it because of her experiences playing professional hockey, and while she is focusing on her new company and the work she is doing, she indicates that she still loves the NHL for her attitude and Will hold him accountable for brain injuries.
“I’m not going anywhere,” he said. “The reason I know so much about them is because of them. So, like, honestly, I can say this, I can lay my head on the pillow, I’m not angry at them. I’m very Thankful that they have. Acted and continue the way they do because it just fuels me. And here we are ready to bring novel care options for TBI survivors. It’s amazing. “
This option is for TBI survivors across the spectrum: athletes, veterans, survivors of domestic violence. And Carcillo wants to show them that they too can get better, and that is the hope. He talks passionately about Psilocybin, because after years of suffering, spending thousands and thousands of dollars, reaching its breaking point, it changed his life for the better. But he is willing to emphasize that psilocybin is no miracle drug – it just “shakes the ice world” – and requires a lot of work to do other than its use.
And, he adds, that people need to wait for science – yes, research – to back-up what he is saying.
He said, “I shouldn’t listen to me. They really shouldn’t do that.” “They should just wait until I work. I’m just telling my story. I don’t need people to listen to me to verify this. That’s why I go through the F.D.A. I am raising hundreds of millions of dollars. The process of validating what has happened to me. That is why we are here. So we are talking and I am going to continue this because I know that it is for the survivors of TBI. is the way. .
“And I will help people. My goal is to help a million people, and I will do so before the end of my life.”
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